Nociception level monitoring

A technology platform to assess the physiological response to pain (nociception), by leveraging composite artificial intelligence algorithms to process and analyzing pain-related physiological parameters.
A non-invasive finger probe records multiple physiological signals through 4 sensors:

  • Temperature;Medasense 2
  • PPG-photoplethysmograph;
  • GSR-Galvanic Skin Response;
  • Accelerometer.

A composite algorithm analyses the data and reflect the information into the nociception level index (NOL™).
The NOL™ is presented on a scale from 0 (no pain) to 100 (extreme pain).

NOL™ is calibrated to the individual and provides continuous real time monitoring and it has the following features:

  • Enables personalized analgesia treatment
  • Optimizes analgesic titration
  • Identifies crisis earlier for faster intervention
  • Reduces practice variability
  • Enables balanced anesthesia (with more stable hemodynamics)

Clinical results indicate that NOL™ discriminates between painful and non-painful stimuli.

NOL™ is produced by Medasense Biometrics Ltd. and exclusively distributed by MOSS S.p.A..



Medasense Biometrics Ltd.
4 Hachilazon St., 7th floor
Ramat Gan 5252268,